Structure determination

Our scientists have extensive expertise and experience with the structure determination and model refinement. Structure determination and data analysis are performed using a special, dedicated software. After resolving the phase issues, model building and refinement are carried out in iterative cycles. R-factors are used as a parameters of model quality. Structure refinement proceeds until the values of R-factors converge to the low, acceptable levels. When refinement is finished the quality of the final model is verified using a special software for structure validation.

After determination of the tertiary structure, the final report is prepared, which includes high-quality figures, microphotographs of the crystal as well as raw crystallographic data.

Upon request, we perform detailed analyses of secondary structures as well as comparative analyses with known protein structure. Please contact us for more information.

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